ea0099ep25 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024
M. Haqq Andrea
, Poitou-Bernert Christine
, Chung Wendy
, Iqbal Anoop
, Forsythe Elizabeth
, Malhotra Sonali
, Touchot Nicolas
, Clement Karine
, Argente Jesus
Background: Patients with Bardet-Biedl syndrome (BBS), a rare syndrome associated with obesity and hyperphagia, commonly manifest traits of metabolic syndrome, including abdominal obesity, impaired fasting glucose, low high-density lipoprotein cholesterol, hypertriglyceridemia, and hypertension. Setmelanotide treatment results in significant improvement in weight, hunger, and quality of life in these patients and may improve measures associated with metabolic syndrome developm...